This defect is a result of partial spray drying or overwetting.

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Multiple Choice

This defect is a result of partial spray drying or overwetting.

Explanation:
Film coating defects are driven by how the coating dries and levels on the tablet surface. When drying is incomplete or too much coating liquid is applied, the film doesn’t form a smooth, continuous layer. Partial spray drying leaves solvent trapped and the outer surface dries unevenly, while overwetting causes pooling and nonuniform drying. The result is an uneven, bumpy surface often described as a rough coating (orange-peel texture). This specific issue points to problems in the coating stage related to evaporation and film formation, rather than dissolution behavior, imprints, or tablet sticking.

Film coating defects are driven by how the coating dries and levels on the tablet surface. When drying is incomplete or too much coating liquid is applied, the film doesn’t form a smooth, continuous layer. Partial spray drying leaves solvent trapped and the outer surface dries unevenly, while overwetting causes pooling and nonuniform drying. The result is an uneven, bumpy surface often described as a rough coating (orange-peel texture). This specific issue points to problems in the coating stage related to evaporation and film formation, rather than dissolution behavior, imprints, or tablet sticking.

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